Dr. Wenliang Lei is currently a principal investigator at Guangdong-HongKong-Macau Institute of CNS Regeneration (GHMICR) in Jinan University. Dr. Lei received his bachelor’s degree in life sciences from Nankai University in 2006, and his Ph.D. in neurobiology form Institute of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences in 2012. Then he completed his 5-year postdoctoral training at the Department of Cell Biology in Emory University. Dr. Lei’s research mainly focuses on the cellular mechanisms of synaptic development and plasticity, the application of cutting-edge bioimaging technologies, the development of non-human primate models for neurodegenerative disorders, and the development of gene therapy for CNS diseases and injuries based on in vivo neuroregeneration. Dr. Lei joined GHMICR in Jinan University in 2018. He has published multiple research articles and reviews in The Journal of Cell Biology, Cell Research, Current Opinion in Neurobiology, The Journal of Neuroscience, The Journal of Biological Chemistry, and Frontiers in Neuroscience. He has been leading several National and Guangdong Natural Science Foundation Programs, participating in Guangdong Grant Key Technologies for Treatment of Brain Disorders. The research grants that have been awarded to him have approached 2 million. He has also been awarded the National Scholarship (1st Class) and the Chinese Academy of Sciences DiAo Scholarship (1st Class).
1. Lineage tracing of direct astrocyte-to-neuron conversion in the mouse cortex, Neural Regeneration Research, 2021
2. Non-engineered and engineered adult neurogenesis in mammalian brains, Frontiers in Neuroscience, 2019
3. Tropomodulin isoform-specific regulation of dendrite development and synapse formation, The Journal of Neuroscience, 2018
4. Phosphoinositide-dependent enrichment of actin monomers in dendritic spines regulates synapse development and plasticity, The Journal of Cell Biology, 2017
5. Actin cytoskeleton in dendritic spine development and plasticity, Current Opinion in Neurobiology, 2016
6. Jip1 mediates anterograde transport of Rab10 cargos during neuronal polarization, The Journal of Neuroscience, 2014
7. Laminin/β1 integrin signal triggers axon formation by promoting microtubule assembly and stabilization, Cell Research, 2012
8. Nuclear factor κB controls acetylcholine receptor clustering at the neuromuscular junction, The Journal of Neuroscience, 2010
9. Wnt/beta-catenin signaling suppresses rapsyn expression and inhibits acetylcholine receptor clustering at the neuromuscular junction, The Journal of Biological Chemistry, 2008
