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首页  Research Achievements  All publications  2018
  • Aberrant Development and Synaptic Transmission of Cerebellar Cortex in a VPA Induced Mouse Autism Model

    Ruanna Wang, Jiahui Tan, Junxiu Guo, Yuhan Zheng, Qing Han, Kwok-Fai So, Jiandong Yu, Li Zhang

    Front Cell Neurosci . 2018 Dec 21;12:500. PMID: 30622458 PMCID: PMC6308145 DOI: 10.3389/fncel.2018.00500

  • Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury

    Qishuang Zhou, Hongkai Xiang, Ang Li, Wu Lin, Zhaoshui Huang, Junxiu Guo, Pingjie Wang, Yijie Chi, Ke Xiang, Yunsheng Xu 1, Libing Zhou, Kwok-Fai So, Xiaoming Chen, Xin Sun, Yi Ren

    PJ Neurotrauma . 2019 Mar 19;36(6):903-918. MID: 30221582 DOI: 10.1089/neu.2018.5783

  • Distribution and Functional Implication of Secretin in Multiple Brain Regions

    Ruanna Wang, Billy K C Chow, Li Zhang

    J Mol Neurosci . 2019 Jul;68(3):485-493. PMID: 29882022 DOI: 10.1007/s12031-018-1089-z

  • CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads to drug-treatable autism-like symptoms

    Zhuchi Tu, Hui Zhao, Bang Li, Sen Yan, Lu Wang, Yongjin Tang, Zhujun Li, Dazhang Bai, Caijuan Li, Yingqi Lin, Yuefeng Li, Jianrong Liu, Hao Xu, Xiangyu Guo, Yong-Hui Jiang, Yong Q Zhang, Xiao-Jiang Li

    Hum Mol Genet . 2019 Feb 15;28(4):561-571. PMID: 30329048 PMCID: PMC6489410 DOI: 10.1093/hmg/ddy367

  • Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy

    Xing Sun, Yongjia Duan, Caixia Qin, Jian-Chiuan Li, Gang Duan, Xue Deng, Jiangxia Ni, Xu Cao, Ke Xiang, Kuili Tian, Chun-Hong Chen, Ang Li, Yanshan Fang

    Cell Death Dis . 2018 Sep 20;9(10):953. PMID: 30237395 PMCID: PMC6148241 DOI: 10.1038/s41419-018-1022-y

  • Carbon nanotube multilayered nanocomposites as multifunctional substrates for actuating neuronal differentiation and functions of neural stem cells

    Han Shao, Tingting Li, Rong Zhu, Xiaoting Xu, Jiandong Yu, Shengfeng Chen, Li Song, Seeram Ramakrishna, Zhigang Lei, Yiwen Ruan, Liumin He

    Biomaterials . 2018 Aug;175:93-109. PMID: 29804001 DOI: 10.1016/j.biomaterials.2018.05.028

  • Piperine ameliorates SCA17 neuropathology by reducing ER stress

    Jifeng Guo, Yiting Cui, Qiong Liu, Yang Yang, Yujing Li, Ling Weng, Beisha Tang, Peng Jin, Xiao-Jiang Li, Su Yang, Shihua Li

    Mol Neurodegener . 2018 Jan 30;13(1):4. PMID: 29378605 PMCID: PMC5789626 DOI: 10.1186/s13024-018-0236-x

  • Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Bradycardiac Effects Caused by Co-Administration of Sofosbuvir and Amiodarone

    Yankun Yu, Feng Liu, Liuming He, Seeram Ramakrishna, Monica Zheng, Lei Bu,Ying Xu

    Assay Drug Dev Technol . May/Jun 2018;16(4):222-229. PMID: 29847141 DOI: 10.1089/adt.2017.834

  • Structural and visual functional deficits in a rat model of neuromyelitis optica spectrum disorders related optic neuritis

    Yuxin Zhang, Yiqin Bao, Wei Qiu, Lisheng Peng, Ling Fang, Ying Xu, Hui Yang

    Exp Eye Res . 2018 Oct;175:124-132. PMID: 29913164 DOI: 10.1016/j.exer.2018.06.011

  • Inhibition of non-NMDA ionotropic glutamate receptors delays the retinal degeneration in rd10 mouse

    Zongqin Xiang, Yiqin Bao, Jia Zhang, Chao Liu, Di Xu, Feng Liu, Hui Chen, Liumin He, Seeram Ramakrishna, Zaijun Zhang, Noga Vardi, Ying Xu

    Neuropharmacology . 2018 Sep 1;139:137-149. PMID: 29940208 DOI: 10.1016/j.neuropharm.2018.06.027

  • Identification of novel binding sites for heparin in receptor protein-tyrosine phosphatase (RPTPσ): Implications for proteoglycan signaling

    Yasuhiro Katagiri, Ashlea A Morgan, Panpan Yu, Nathanael J Bangayan, Radoslaw Junka, Herbert M Geller

    J Biol Chem . 2018 Jul 20;293(29):11639-11647. PMID: 29880643 PMCID: PMC6065195 DOI: 10.1074/jbc.RA118.003081

  • Effect of chondroitin sulfate proteoglycans on neuronal cell adhesion, spreading and neurite growth in culture

    Jingyu Jin, Sharada Tilve, Haiphong Huang, Libing Zhou, Herbert M Geller, Panpan Yu

    Neural Regen Res . 2018 Feb;13(2):289-297. PMID: 29557379 PMCID: PMC5879901 DOI: 10.4103/1673-5374.226398

  • Lycium Barbarum Polysaccharides Protect Retina in rd1 Mice During Photoreceptor Degeneration

    Feng Liu, Jia Zhang, Zongqin Xiang, Di u, Kwok-Fai So, Noga Vardi, Ying Xu

    Invest Ophthalmol Vis Sci . 2018 Jan 1;59(1):597-611. PMID: 29372259 PMCID: PMC6623178 DOI: 10.1167/iovs.17-22881

  • Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues

    Hei Ming Lai, Alan King Lun Liu, Harry Ho Man Ng, Marc H Goldfinger, Tsz Wing Chau, John DeFelice, Bension S Tilley, Wai Man Wong, Wutian Wu, Steve M Gentleman

    Nat Commun . 2018 Mar 14;9(1):1066. PMID: 29540691 PMCID: PMC5852003 DOI: 10.1038/s41467-018-03359-w

  • Flexible Roles for Proteoglycan Sulfation and Receptor Signaling

    Panpan Yu, Craig S Pearson, Herbert M Geller

    Trends Neurosci . 2018 Jan;41(1):47-61. PMID: 29150096 PMCID: PMC5748001 DOI: 10.1016/j.tins.2017.10.005

  • Dual extra-retinal origins of microglia in the model of retinal microglia repopulation

    Yubin Huang, Zhen Xu, Shanshan Xiong, Guangrong Qin, Fangfang Sun, Jian Yang, Ti-Fei Yuan, Lei Zhao, Ke Wang, Yu-Xiang Liang, Lin Fu, Tianzhun Wu, Kwok-Fai So, Yanxia Rao, Bo Peng

    Cell Discov . 2018 Feb 27;4:9. PMID: 29507754 PMCID: PMC5827656 DOI: 10.1038/s41421-018-0011-8

  • Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

    YB Huang, Z Xu, SS Xiong, FF Sun, GR Qin, GL Hu, JJ Wang, L Zhao, YX Liang, TZ Wu, ZH Lu, Mark S. Humayun, KF So, YH Pan, NN Li, TF Yuan, YX Rao and B Peng

    Nat Neurosci . 2018 Apr;21(4):530-540. doi: 10.1038/s41593-018-0090-8. Epub 2018 Feb 22.

  • γδ T cells provide the early source of IFN-γ to aggravate lesions in spinal cord injury

    Sun G, Yang S, Cao G, Wang Q, Hao J, Wen Q, Li Z, So KF, Liu Z, Zhou S, Zhao Y, Yang H, Zhou L*, Yin Z*

    J Exp Med . 2018 Feb 5;215(2):521-535. doi: 10.1084/jem.20170686. Epub 2017 Dec 27.

  • A huntingtin knock-in pig model recapitulates features of selective neurodegeneration in Huntington's disease

    Sen Yan#, Tu ZC#, Liu ZM#, Li S*,Lai LX*, Li XJ*

    Cell . 2018 May 3;173(4):989-1002.e13. doi: 10.1016/j.cell.2018.03.005. Epub 2018 Mar 29.

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