Dr. Li Lin

Release time:2018-10-30 Publishing unit:粤港澳中枢神经再生研究院

Introduction


Dr. Li Lin received her Ph.D. in Biochemistry and Molecular Biology in 2007 from China Agricultural University. Then she accomplished her postdoctoral training in the Department of Human Genetics, Emory University School of Medicine and in Department of Environmental Health, The T. H. Chan School of Public Health, Harvard University. In 2016, she joined the GHM Institute of CNS Regeneration, Jinan University. Her research majorly focus on epigenetics, especially on the role of 5-methycytosine and 5-hydromethycytosine in neurodegenerative diseases. By screening abnormal DNA methylation sites, to select epigenetic biomarkers for pathomechanism and treatment of those disease.


Selected Publications


1. Lin, L., Hales, C.M., Garber, K. and Jin, P. (2014) Fat mass and obesity-associated (FTO) protein interacts with CaMKII and modulates the activity of CREB signaling pathway. Human molecular genetics, 23, 3299-3306.

2. Li, Y*., Lin, L*., (equal contribution), Li, Z., Ye, X., Xiong, K., Aryal, B., Xu, Z., Paroo, Z., Liu, Q., He, C. et al. (2012) Iron homeostasis regulates the activity of the microRNA pathway through poly(C)-binding protein 2. Cell metabolism, 15, 895-904.

3. Lin, L., Vitale,A.V. and Jin, P. (2010) Small RNAs in Neurological Disorders. Encyclopedia of Life Sciences (ELS) , DOI: 10.1002/9780470015902.a0022385

4. Lin, L., Xu, W., Dai, Y. and Li, N. (2009) DNA methylation changes in cell line from beta-lactoglobulin gene targeted fetus. Animal reproduction science, 112, 402-408.

5. Lin, L. *, Li, Q. *, (equal contribution)Zhang, L., Zhao, D., Dai, Y. and Li, N. (2008) Aberrant epigenetic changes and gene expression in cloned cattle dying around birth. BMC developmental  biology, 8, 14.