Wutian Wu, MD, PhD, Professor and Associate director, GHM Institute of CNS Regeneration, Jinan University, Guangzhou, China. Professor Wutian Wu, received his MD, MS degree from Sun Yat-Sun University Medical Sciences, Guangzhou, China in 1975 and 1981 respectively. He received his PhD degree from Eastern Virginia Medical School, Virginia, USA in 1991. Since 1996, Dr. Wu has been working as assistant professor to professor in the Department of Anatomy, LKS Faculty of Medicine, the University of Hong Kong. He is the associate director of the State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong; associate director of GHM Institute of CNS Regeneration, Jinan University, Guangzhou. His research has been focusing on neuronal injury and neurodegenerative diseases. In addition to study mechanisms underlying neuronal degeneration in neuronal injury and diseases, he has also been studying potential approaches to improve neuronal survival, axonal regeneration and functional recovery by using small molecule drugs, stem cells and biomaterials. He has received over 40 research grants from NIH, Hong Kong Research gran council and China government. Professor Wu has published over 170 peer review papers in international journals such as Nature Medicine, Nature Neuroscience, Nature Methods, Nature Communication, PNAS, Development, Nanomedicine etc. and received good citation. His “H” index is around 50. As keynote speaker, he has been invited to give talk for more than 60 international conferences. He was invited to prepare a chapter for a volume in the series Handbook of Chemical Neuroanatomy with Dr. L. J. Ignarro together who was the Winner of the 1998 Nobel Prize in Medicine. Professor Wu’s research in spinal cord injury has received a Chinese National Award (2nd price). He has participated in several clinical trials in spinal cord injury.
1. Wu W*: Expression of nitric oxide synthase in injured CNS neurons as shown by NADPH-diaphorase histochemistry. Exp. Neurol. 120:153-159, 1993.
2. Wu W* and Li, L.: Inhibition of nitric oxide synthase reduces death of spinal motoneu¬rons due to avulsion lesion. Neurosci. Lett. 153(2):121-124, 1993.
3. Li L, Wu W, Oppenheim RW, Lin LFH, Lei M and Houenou LJ: Rescue of adult mouse motoneurons from injury-induced cell death by a glial cell line-derived neurotrophic factor (GDNF). P. Natl. Acad. Sci. USA. 92:9771-9775, 1995.
4. Yick LW, Wu W*, So KF and Shum DKY: Chondroitinase ABC promotes axonal regeneration of Clarkes neurons after spinal cord injury. NeuroReport, 11:1063-1067, 2000.
5. Wu W*, Li L, Yick LW, Chai H, Xie YY, Yang Y, Prevette DM and Oppenheim RW: GDNF and BDNF alter the expression of NOS, c-Jun, and p75 and prevent motoneuron death following spinal root avulsion. J. Neurotrauma 20(6):603-612, 2003.
6. Yick LW, Cheung PT, So KF and Wu W*: Axonal regeneration of Clarke¡|s neurons beyond the spinal cord injury scar after treatment with chondroitinase ABC. Exp. Neurol. 182:160-168, 2003.
7. Mi S, Hu B, Hahm K, Luo Y, Hui SK, Yuan Q, Wong WM, Wang L, Su HX, Chu TH, Guo JS, Zhang WM, So KF, Pepinsky B, Shao ZH, Graff C, Garber E, Jung V, Wu XK, Wu W*: LINGO-1 Antagonist Promotes Spinal Cord Remyelination and Axonal Integrity in MOG-Induced Experimental Autoimmune Encephalomyelitis. Nature Medicine, 13:1228-1233, 2007.
